Injectables Basics: Botox vs. Fillers
- almeidakrysten
- Apr 25
- 2 min read
Updated: Apr 25
What is Botox, what are fillers, and which one do you want?

I am going to give you a brief, yet informative overview of the two, pulling from my background in biochemistry, histology, and anatomy.
“Botox” is an overarching term for “neurotoxins.” Botox cosmetic was the first FDA approved “neurotoxin” derived from Clostridium botulinum.
Neurotoxins
Neurotoxins address lines at rest (lines on the face when not moving) and prevent the skin from folding and creasing by relaxing the muscles. Neurotoxins work to stop the transmission of acetylcholine, which is the neurotransmitter responsible for muscle movement. Neurotoxins address areas of high mobility and muscle activity in those areas. They can also cause a “slimming” effect, especially along the jawline. Neurotoxins also address non-cosmetic concerns, such as bruxism (teeth grinding), TMJ, and hyperhidrosis (excessive sweating).
Fillers
Fillers work by adding volume to an area. Fine lines and deeper creases can be filled in with a gel-like substance, composed of hyaluronic acid. We all have hyaluronic acid in our bodies, and the type that we get injected as a “filler” is synthetic. The purpose of fillers is to replete volume lost with age. The first area we see that loses volume is the cheeks in our early twenties, followed by a falling cupid's bow, and oral commissures (corners of the mouth). The purpose of filler is to provide support, allowing for lasting results.
The aging process
As we age, we lose volume and density, and muscle begins to separate from the fascia holding it to internal structures. As early as our 20’s, when we begin to lose estrogen, that loss creates a cascade of changes. At that point, we begin to lose collagen, and in turn a decrease in subcutaneous tissue and bone density.
What can we do to prevent aging and maintain healthy habits so we look good and feel good?
There are several ways to maintain our skin and physical health so we look good and feel good. One major way is to wear SPF to combat UV rays and free radicals and prevent skin cancers. UV rays cause damage to the skin layers which compromises its integrity. Skin’s reaction to the sun’s rays is to become hyperpigmented, which is why we can get dark spots from sun exposure. By staying hydrated and maintaining a healthy diet, we can keep our bodies nourished, keeping our skin looking young and fresh! After all, our skin health is correlated with our gut health.
Nevertheless, it is a privilege to age and endure the changes in our bodies. However, my priority as an aesthetic nurse is to help you meet your standards and goals that help you feel better. Whether that is with a wellness vitamin shot, tinted sunscreen, Botox injections, or adding volume back to areas where it was lost, I am here for the journey!
Are you interested in Botox or fillers?
Botox
Fillers
Both
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